• The recent transfer of a homing endonuclease gene 

      Haugen, Peik; Wikmark, Odd-Gunnar; Vader, Anna; Coucheron, Dag H.; Sjøttem, Eva; Johansen, Steinar D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
      The myxomycete Didymium iridis (isolate Panama 2) contains a mobile group I intron named Dir.S956-1 after position 956 in the nuclear small subunit (SSU) rRNA gene. The intron is efficiently spread through homing by the intron-encoded homing endonuclease I-DirI. Homing endonuclease genes (HEGs) usually spread with their associated introns as a unit, but infrequently also spread independent of ...
    • Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron 

      Wikmark, Odd-Gunnar; De Jonckheere, Johan F.; Einvik, Christer; Johansen, Steinar D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-05-02)
      Background Ribosomal DNA of several species of the free-living Naegleria amoeba harbors an optional group I intron within the nuclear small subunit ribosomal RNA gene. The intron (Nae.S516) has a complex organization of two ribozyme domains (NaGIR1 and NaGIR2) and a homing endonuclease gene (NaHEG). NaGIR2 is responsible for intron excision, exon ligation, and full-length intron RNA circularization, ...
    • Tn1546 is part of a larger plasmid-encoded genetic unit horizontally disseminated among clonal Enterococcus faecium lineages 

      Sletvold, H; Johnsen, PJ; Wikmark, Odd-Gunnar; Simonsen, Gunnar Skov; Sundsfjord, A; Nielsen, KM (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      o determine the genetic composition of the first VanA-type plasmid (pIP816) reported, which was isolated from a clinical Enterococcus faecium (BM4147) strain in France in 1986, and to reveal the genetic units responsible for the dissemination of the vanA gene cluster by comparisons with current, published and additionally generated vanA-spanning plasmid sequences obtained from a heterogeneous E. ...